Tablet Manufacturer/Distributor: Acme Specialized Pharmaceuticals Ltd. Generic Name: Cetirizine Dihydrochloride 10mg
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Indications of Cetizin 10
It's used to treat seasonal and perennial allergic rhinitis symptoms. It's also used to treat the cutaneous symptoms of chronic idiopathic urticaria and allergen-induced asthma.
Pharmacology
Cetirizine Hydrochloride may be a powerful H1 receptor enemy without any noteworthy anticholinergic and antiserotonic impacts. At pharmacologically dynamic measurements levels, it has nearly no laziness impact and does not cause behavioral changes. It represses the histamine-mediated early stage of the unfavorably susceptible response additionally diminishes the relocation of provocative cells and the discharge of go betweens related with the late stage of the unfavorably susceptible response.
Pharmacokinetics: Cetirizine 10 mg accomplishes top plasma concentrations of 257 mcg/L inside one hour of organization (980 mcg/L in children). Nourishment does not influence the degree of retention, but it may marginally decrease the rate. Top blood levels 0.3 micrograms/ml are come to between thirty & sixty minutes after organization of 10 mg dosage of Cetirizine. Its plasma half-life is roughly 11 hours. Assimilation is exceptionally steady from one subject to the following. Its renal clearance is 30 ml/minute and the excretion half-life is around nine hours.
Dosage & Administration
Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily (or 1 teaspoonful twice daily).
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily.
Children 6 months to 2 years : 1/2 teaspoonful once daily. The dose in children 12-23 months of age can be increased to a maximum dose as 1/2 teaspoonful every 12 hours.
Interaction of Cetizin 10
Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, and Erythromycin, as well as other medications, have been determined to have no clinically relevant drug interactions.
Contraindications
Patients with a history of Cetirizine or hydroxyzine hypersensitivity should avoid it.
Side Effects of Cetizin 10
Somnolence is one of the most common side effects associated with Cetirizine.
Pregnancy & Lactation
Cetirizine Hydrochloride is classified as a pregnancy category B by the US Food and Drug Administration. However, no suitable and well-controlled studies on pregnant women have been conducted. Because animal reproduction studies do not always predict human response, this medication should only be used during pregnancy if absolutely necessary. Human milk has been found to contain cetirizine hydrochloride. When Cetirizine Hydrochloride is given to a breastfeeding woman, caution should be observed.
Precautions & Warnings
When driving an automobile or operating heavy machinery, extreme caution is advised.
Storage Conditions
Keep away from light and heat in a dry location. Keep out of children's reach.
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